WB analysis of various samples using GTX01531 FANCD2 antibody [GT1223]. Dilution : 1:1000 Loading : 25 microg
FANCD2 antibody [GT1223] - Orthogonal Validated
GTX01531
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetFANCD2
Overview
- SupplierGeneTex
- Product NameFANCD2 antibody [GT1223] - Orthogonal Validated
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT1223
- ConjugateUnconjugated
- Gene ID2177
- Target nameFANCD2
- Target descriptionFA complementation group D2
- Target synonymsFA4; FACD; FAD; FAD2; FA-D2; FANCD; Fanconi anemia complementation group D2; Fanconi anemia group D2 protein
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203