Fascin 1 antibody [IM20]

GeneTex

Fascin 1 antibody [IM20]

9

WB: 1:100-1:200. IHC-P: 1:200-1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

IM20

Unconjugated

FSCN1

fascin actin-bundling protein 1

FAN1, HSN, SNL, p55, fascin, 55 kDa actin-bundling protein, epididymis secretory sperm binding protein, fascin homolog 1, actin-bundling protein, singed-like (fascin homolog, sea urchin)

Mouse

IgG1

Fascin

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkins lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

Human

2°C to 8°C

12352203