Fascin 1 antibody [ZM192]

GeneTex

Fascin 1 antibody [ZM192]

9

IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

ZM192

Unconjugated

FSCN1

fascin actin-bundling protein 1

55 kDa actin-bundling protein; epididymis secretory sperm binding protein; FAN1; fascin; fascin homolog 1, actin-bundling protein; HSN; p55; singed-like (fascin homolog, sea urchin); SNL

Mouse

IgG2a

Fascin

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkins lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

Human

2°C to 8°C

12352203