Fatty Acid Synthase antibody [N1], N-term
GTX109833
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetFASN
Overview
- SupplierGeneTex
- Product NameFatty Acid Synthase antibody [N1], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID2194
- Target nameFASN
- Target descriptionfatty acid synthase
- Target synonymsFAS, OA-519, SDR27X1, fatty acid synthase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, 3-oxoacyl-[acyl-carrier-protein] reductase, 3-oxoacyl-[acyl-carrier-protein] synthase, Acyl-[acyl-carrier-protein] hydrolase, Enoyl-[acyl-carrier-protein] reductase, [Acyl-carrier-protein] S-acetyltransferase, [Acyl-carrier-protein] S-malonyltransferase, short chain dehydrogenase/reductase family 27X, member 1, type I fatty acid synthase
- HostRabbit
- IsotypeIgG
- Protein IDP49327
- Protein NameFatty acid synthase
- Scientific DescriptionThe enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Giuliani A, Giudetti AM, Vergara D, et al. Senescent Endothelial Cells Sustain Their Senescence-Associated Secretory Phenotype (SASP) through Enhanced Fatty Acid Oxidation. Antioxidants (Basel). 2023,12(11). doi: 10.3390/antiox12111956Read this paper
- Ceja-Galicia ZA, García-Arroyo FE, Aparicio-Trejo OE, et al. Therapeutic Effect of Curcumin on 5/6Nx Hypertriglyceridemia: Association with the Improvement of Renal Mitochondrial β-Oxidation and Lipid Metabolism in Kidney and Liver. Antioxidants (Basel). 2022,11(11). doi: 10.3390/antiox11112195Read this paper
- Tsao CH, Jhou RH, Ke CC, et al. Dual-tracer positron emission tomography/computed tomography as an imaging probe of de novo lipogenesis in preclinical models of hepatocellular carcinoma. Front Med (Lausanne). 2022,9:1008200. doi: 10.3389/fmed.2022.1008200Read this paper
- Raineri A, Campagnari R, Dal Toso R, et al. 3,5-Dicaffeoylquinic Acid Lowers 3T3-L1 Mitotic Clonal Expansion and Adipocyte Differentiation by Enhancing Heme Oxygenase-1 Expression. Molecules. 2021,26(16). doi: 10.3390/molecules26165027Read this paper
- Park S, Song J, Baek IJ, et al. Loss of Acot12 contributes to NAFLD independent of lipolysis of adipose tissue. Exp Mol Med. 2021,53(7):1159-1169. doi: 10.1038/s12276-021-00648-1Read this paper
- Tsai YT, Ruan JW, Chang CS, et al. Antrodia cinnamomea Confers Obesity Resistance and Restores Intestinal Barrier Integrity in Leptin-deficient Obese Mice. Nutrients. 2020,12(3). doi: 10.3390/nu12030726Read this paper
- García-Arroyo FE, Monroy-Sánchez F, Muñoz-Jiménez I, et al. Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats. Biomolecules. 2019,9(10). doi: 10.3390/biom9100601Read this paper
- Ezzeddini R, Taghikhani M, Somi MH, et al. Clinical importance of FASN in relation to HIF-1α and SREBP-1c in gastric adenocarcinoma. Life Sci. 2019,224:169-176. doi: 10.1016/j.lfs.2019.03.056Read this paper
- You BJ, Hour MJ, Chen LY, et al. Fenofibrate induces human hepatoma Hep3B cells apoptosis and necroptosis through inhibition of thioesterase domain of fatty acid synthase. Sci Rep. 2019,9(1):3306. doi: 10.1038/s41598-019-39778-yRead this paper
- Shimada M, Hibino M, Takeshita A. Dietary supplementation with myo-inositol reduces hepatic triglyceride accumulation and expression of both fructolytic and lipogenic genes in rats fed a high-fructose diet. Nutr Res. 2017,47:21-27. doi: 10.1016/j.nutres.2017.08.005Read this paper
Datasheet
Related products
Product group Antibodies
Fatty Acid Synthase Recombinant AntibodyBSM-54469R
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetFASN
- SizePrice
Product group Antibodies
Fasn Polyclonal AntibodyCAC07284
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
TargetFASN
- SizePrice
Product group Antibodies
Fatty Acid Synthase (FASN) AntibodyABX301365
ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
- SizePrice
Product group Antibodies
Anti-FASN Antibody144-00461
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
TargetFASN
- SizePrice
Product group Antibodies
ApplicationsWestern Blot, ELISA
- SizePrice
Product group Antibodies
Fatty Acid Synthase antibody [GT237]GTX629628
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetFASN
- SizePrice
Product group Antibodies
Fatty Acid Synthase antibody [GT325]GTX629629
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
TargetFASN
- SizePrice
Product group Antibodies
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
TargetFASN
- SizePrice
Product group Antibodies
Fatty Acid Synthase antibody [GT556]GTX629762
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetFASN
- SizePrice