FCGRT / FcRn (IgG Transporter)(FCGRT/2932), CF647 conjugate, 0.1mg/mL [26628-22-8]

Biotium

FCGRT / FcRn (IgG Transporter)(FCGRT/2932), CF647 conjugate, 0.1mg/mL [26628-22-8]

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

26628-22-8

Research Use Only

Monoclonal

FCGRT/2932

0.1 mg/ml

Other Conjugate

FCGRT

Fc gamma receptor and transporter

FCRN, FcgammaRn, alpha-chain, IgG receptor FcRn large subunit p51, Fc fragment of IgG receptor and transporter, Fc fragment of IgG, receptor, transporter, alpha, FcRn alpha chain, IgG Fc fragment receptor transporter alpha chain, heavy chain of the major histocompatibility complex class I-like Fc receptor, immunoglobulin receptor, intestinal, heavy chain, major histocompatibility complex class I-like Fc receptor, neonatal Fc receptor, neonatal Fc-receptor for Ig, neonatal fragment crystallizable Fc receptor FcRn, transmembrane alpha chain of the neonatal receptor

Mouse

IgG2b

IgG receptor FcRn large subunit p51

This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C,RT

41116161