FKBP4 Polyclonal Antibody

Reddot Biotech

FKBP4 Polyclonal Antibody

5

1.14 mg/ml

FKBP4

FKBP prolyl isomerase 4

FK506 binding protein 4, 59kDa; FKBP51; FKBP52; FKBP59; HBI; HSP binding immunophilin; Hsp56; p52; peptidylprolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase FKBP4; PPIase; rotamase; T-cell FK506-binding protein, 59kD

FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimers,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.

-20°C

12352203