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FOXA1 antibody

GTX100308
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityFish, Human
TargetFOXA1
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Overview

  • Supplier
    GeneTex
  • Product Name
    FOXA1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.44 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3169
  • Target name
    FOXA1
  • Target description
    forkhead box A1
  • Target synonyms
    forkhead box protein A1; hepatocyte nuclear factor 3-alpha; HNF3A; HNF-3A; HNF-3-alpha; TCF3A; TCF-3A; transcription factor 3A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP55317
  • Protein Name
    Hepatocyte nuclear factor 3-alpha
  • Scientific Description
    This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq]
  • Reactivity
    Fish, Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma.
    Read more
  • Systematic Dissection of Sequence Features Affecting the Binding Specificity of a Pioneer Factor Reveals Binding Synergy Between FOXA1 and AP-1.
    Read more
  • Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers. Lemma RB et al., 2022 Apr 19, Epigenetics Chromatin
    Read more
  • Pan-cancer predictions of transcription factors mediating aberrant DNA methylation. Detilleux D et al., 2022 Mar 24, Epigenetics Chromatin
    Read more
  • DNA methylation modification is associated with gonadal differentiation in Monopterus albus. Wang X et al., 2020 Nov 10, Cell Biosci
    Read more
  • FOXA1 transcriptionally up-regulates cyclin B1 expression to enhance chondrosarcoma progression. Lin ZS et al., 2018, Am J Cancer Res
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  • Resources for the Comprehensive Discovery of Functional RNA Elements. Sundararaman B et al., 2016 Mar 17, Mol Cell
    Read more