FOXA1 antibody
GTX100308
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetFOXA1
Overview
- SupplierGeneTex
- Product NameFOXA1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.44 mg/ml
- ConjugateUnconjugated
- Gene ID3169
- Target nameFOXA1
- Target descriptionforkhead box A1
- Target synonymsforkhead box protein A1; hepatocyte nuclear factor 3-alpha; HNF3A; HNF-3A; HNF-3-alpha; TCF3A; TCF-3A; transcription factor 3A
- HostRabbit
- IsotypeIgG
- Protein IDP55317
- Protein NameHepatocyte nuclear factor 3-alpha
- Scientific DescriptionThis gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma.Read more
- Systematic Dissection of Sequence Features Affecting the Binding Specificity of a Pioneer Factor Reveals Binding Synergy Between FOXA1 and AP-1.Read more
- Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers. Lemma RB et al., 2022 Apr 19, Epigenetics ChromatinRead more
- Pan-cancer predictions of transcription factors mediating aberrant DNA methylation. Detilleux D et al., 2022 Mar 24, Epigenetics ChromatinRead more
- DNA methylation modification is associated with gonadal differentiation in Monopterus albus. Wang X et al., 2020 Nov 10, Cell BiosciRead more
- FOXA1 transcriptionally up-regulates cyclin B1 expression to enhance chondrosarcoma progression. Lin ZS et al., 2018, Am J Cancer ResRead more
- Resources for the Comprehensive Discovery of Functional RNA Elements. Sundararaman B et al., 2016 Mar 17, Mol CellRead more
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![WB analysis of HEK293T cells transfected with FOXA1 plasmid (Right) or empty vector (Left) for 48 hrs using GTX84486 FOXA1 antibody [3C1]. Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX84486/GTX84486_4398_WB_w_23061420_948.webp)