Overview
- SupplierGeneTex
- Product NameG9a antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.34 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response. Luo CW et al., 2017 Sep, Radiother OncolRead more
- Preprogramming therapeutic response of PI3K/mTOR dual inhibitor via the regulation of EHMT2 and p27 in pancreatic cancer. Tian YF et al., 2018, Am J Cancer ResRead more
- Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1alpha and APC2 gene expression in non-small cell lung cancer. Zhang K et al., 2018 Oct 22, Mol CancerRead more