GAB2 (phospho Tyr643) antibody

GeneTex

GAB2 (phospho Tyr643) antibody

9

WB: 1:500-1:1000. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

GAB2

GRB2 associated binding protein 2

Grb2-associated binder 2; GRB2-associated-binding protein 2; growth factor receptor bound protein 2-associated protein 2; pp100

Rabbit

IgG

GRB2-associated-binding protein 2

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]

Human

-20°C or -80°C,2°C to 8°C

12352203