Western blot analysis of extracts of various cell lines using GAD65/GAD2 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using GAD65/GAD2 Polyclonal Antibody at 1:1000 dilution.
GAD2 Polyclonal Antibody
E-AB-60117
Product group Antibodies
Overview
- SupplierElabscience
- Product NameGAD2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
- UNSPSC12352203