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IHC-P analysis of rat brain tissue using GTX32615 GAD65 antibody. Blue : DAPI Dilution : 1:100
IHC-P analysis of rat brain tissue using GTX32615 GAD65 antibody. Blue : DAPI Dilution : 1:100
IHC-P analysis of rat brain tissue using GTX32615 GAD65 antibody. Blue : DAPI Dilution : 1:100

GAD65 antibody

GTX32615
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGAD2
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Overview

  • Supplier
    GeneTex
  • Product Name
    GAD65 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID2572
  • Target name
    GAD2
  • Target description
    glutamate decarboxylase 2
  • Target synonyms
    GAD65, glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase-2 (pancreas), glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ05329
  • Protein Name
    Glutamate decarboxylase 2
  • Scientific Description
    This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Martirosian V, Deshpande K, Zhou H, et al. Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination. Cell Rep. 2021,35(13):109302. doi: 10.1016/j.celrep.2021.109302
    Read this paper

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