GAD65 antibody [GAD2/1960]

GeneTex

GAD65 antibody [GAD2/1960]

9

IHC-P: 0.1-0.2microg/ml for 30 min at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application

Research Use Only

Monoclonal

GAD2/1960

0.2 mg/ml

Unconjugated

Liquid

GAD2

glutamate decarboxylase 2

65 kDa glutamic acid decarboxylase; GAD65; GAD-65; glutamate decarboxylase 2; glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); Glutamate decarboxylase-2 (pancreas)

Mouse

IgG2b

Glutamate decarboxylase 2

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203