
WB analysis of extracts from Jurkat cells treated with PMA using GTX55401 GADD153 (phospho Ser30) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
GADD153 (phospho Ser30) antibody
GTX55401
ApplicationsWestern Blot
Product group Antibodies
TargetDDIT3
Overview
- SupplierGeneTex
- Product NameGADD153 (phospho Ser30) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1649
- Target nameDDIT3
- Target descriptionDNA damage inducible transcript 3
- Target synonymsAltDDIT3, C/EBPzeta, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153, DNA damage-inducible transcript 3 protein, C/EBP zeta, CCAAT/enhancer-binding protein homologous protein, alternative DDIT3 protein, c/EBP-homologous protein 10, growth arrest and DNA damage-inducible protein GADD153
- HostRabbit
- IsotypeIgG
- Protein IDP35638
- Protein NameDNA damage-inducible transcript 3 protein
- Scientific DescriptionThis gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation.Read more
![WB analysis of 30 ug of whole cell lysates from undifferentiated 3T3-L1 fibroblasts (Fib) and 3T3-L1 fibroblasts differentiated into adipocytes (Day 2 and Day 9 post-differentiation) using GTX11419 GADD153 antibody [9C8]. 3T3-L1 fibroblasts were cultured in differentiation medium for 3 days to generate adipocytes. Differentiated adipocytes were maintained in maturation media containing either 5mM glucose (normal glucose) or 30mM glucose (high glucose). Dilution : 1:1000](https://www.genetex.com/upload/website/prouct_img/normal/GTX11419/GTX11419_1466_WB_w_23060501_426.webp)



