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GADD34 antibody [N1N3]

GTX115747
GeneTex
ApplicationsWestern Blot
Product group Antibodies
TargetPPP1R15A
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Overview

  • Supplier
    GeneTex
  • Product Name
    GADD34 antibody [N1N3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23645
  • Target name
    PPP1R15A
  • Target description
    protein phosphatase 1 regulatory subunit 15A
  • Target synonyms
    GADD34, protein phosphatase 1 regulatory subunit 15A, growth arrest and DNA damage-inducible protein GADD34, growth arrest and DNA-damage-inducible 34, myeloid differentiation primary response protein MyD116 homolog, protein phosphatase 1, regulatory (inhibitor) subunit 15A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75807
  • Protein Name
    Protein phosphatase 1 regulatory subunit 15A
  • Scientific Description
    This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Ho KH, Lee YT, Chen PH, et al. Guanabenz Sensitizes Glioblastoma Cells to Sunitinib by Inhibiting GADD34-Mediated Autophagic Signaling. Neurotherapeutics. 2021,18(2):1371-1392. doi: 10.1007/s13311-020-00961-z
    Read this paper
  • Teng Y, Gao M, Wang J, et al. Inhibition of eIF2α dephosphorylation enhances TRAIL-induced apoptosis in hepatoma cells. Cell Death Dis. 2014,5(2):e1060. doi: 10.1038/cddis.2014.24
    Read this paper

Datasheet

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