
WB analysis of mouse liver tissue lysate using GTX54090 GADD45A antibody. The signal was developed with ECL plus-Enhanced. Dilution : 1:1000 Loading : 25microg per lane
GADD45A antibody
GTX54090
ApplicationsWestern Blot
Product group Antibodies
TargetGADD45A
Overview
- SupplierGeneTex
- Product NameGADD45A antibody
- Delivery Days Customer7
- Application Supplier NoteWB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1647
- Target nameGADD45A
- Target descriptiongrowth arrest and DNA damage inducible alpha
- Target synonymsDDIT1, GADD45, growth arrest and DNA damage-inducible protein GADD45 alpha, DDIT-1, DNA damage-inducible transcript 1 protein, DNA damage-inducible transcript-1, growth arrest and DNA-damage-inducible 45 alpha
- HostRabbit
- IsotypeIgG
- Protein IDP24522
- Protein NameGrowth arrest and DNA damage-inducible protein GADD45 alpha
- Scientific DescriptionThis gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- You W, Xu Z, Sun Y, et al. GADD45α drives brown adipose tissue formation through upregulating PPARγ in mice. Cell Death Dis. 2020,11(7):585. doi: 10.1038/s41419-020-02802-5Read this paper
- Liu SY, Ma YL, Hsu WL, et al. Protein inhibitor of activated STAT1 Ser(503) phosphorylation-mediated Elk-1 SUMOylation promotes neuronal survival in APP/PS1 mice. Br J Pharmacol. 2019,176(11):1793-1810. doi: 10.1111/bph.14656Read this paper






