Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GADD45B Polyclonal Antibody at dilution 1:40
GADD45B Polyclonal Antibody
E-AB-15054
Product group Antibodies
Overview
- SupplierElabscience
- Product NameGADD45B Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.6mg/ml
- Scientific DescriptionThis gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
- UNSPSC12352203