Ganglioside GM2 Asialo Mixture
ORB1984920
CAS Number35960-33-9
Product group Chemicals
Estimated Purity98.00%
Molecular Weight1093.444
Overview
- SupplierBiorbyt
- Product NameGanglioside GM2 Asialo Mixture [35960-33-9]
- Delivery Days Customer10
- CAS Number35960-33-9
- CertificationResearch Use Only
- Estimated Purity98.00%
- Molecular FormulaC56H104N2O18
- Molecular Weight1093.444
- Scientific DescriptionGanglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal beta-hexosaminidase A and B, respectively. It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients. Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable lengths.
- SMILESCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3NC(C)=O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)[C@H](O)\C=C\CCCCCCCCCCCCC
- Storage Instruction-20°C
- UNSPSC12352200