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GCN5 antibody [C2C3], C-term

Research Use Only
GTX114428
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetKAT2A
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Overview

  • Supplier
    GeneTex
  • Product Name
    GCN5 antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody was raised against KAT2A protein, and based on sequence homology, it may cross react with KAT2B protein.
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID2648
  • Target name
    KAT2A
  • Target description
    lysine acetyltransferase 2A
  • Target synonyms
    GCN5; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5L2; general control of amino acid synthesis protein 5-like 2; General control of amino acid synthesis, yeast, homolog-like 2; hGCN5; histone acetyltransferase GCN5; histone acetyltransferase KAT2A; histone glutaryltransferase KAT2A; histone succinyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; PCAF-b; STAF97
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92830
  • Protein Name
    Histone acetyltransferase KAT2A
  • Scientific Description
    KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • USP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy. Wang SA et al., 2020 Nov 30, Sci Rep
    Read more