WB analysis of 293T lysates (50ug) using Geminin antibody at a dilution of 1:500.
WB analysis of 293T lysates (50ug) using Geminin antibody at a dilution of 1:500.
Geminin antibody [2H7]
GTX53720
Overview
- SupplierGeneTex
- Product NameGeminin antibody [2H7]
- Delivery Days Customer9
- Application Supplier NoteThe antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2H7
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID51053
- Target nameGMNN
- Target descriptiongeminin DNA replication inhibitor
- Target synonymsGem; geminin; MGORS6
- HostMouse
- IsotypeIgG1
- Protein IDO75496
- Protein NameGeminin
- Scientific DescriptionThis gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203