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GFAP antibody

Research Use Only
GTX108711
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGFAP
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Overview

  • Supplier
    GeneTex
  • Product Name
    GFAP antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:50000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.47 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID2670
  • Target name
    GFAP
  • Target description
    glial fibrillary acidic protein
  • Target synonyms
    ALXDRD; glial fibrillary acidic protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP14136
  • Protein Name
    Glial fibrillary acidic protein
  • Scientific Description
    This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Fermented Mentha arvensis administration provides neuroprotection against transient global cerebral ischemia in gerbils and SH-SY5Y cells via downregulation of the MAPK signaling pathway. Islam MS et al., 2022 Jun 25, BMC Complement Med Ther
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  • Conducting molybdenum sulfide/graphene oxide/polyvinyl alcohol nanocomposite hydrogel for repairing spinal cord injury. Chen L et al., 2022 May 6, J Nanobiotechnology
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  • Transcranial photobiomodulation (808 nm) attenuates pentylenetetrazole-induced seizures by suppressing hippocampal neuroinflammation, astrogliosis, and microgliosis in peripubertal rats. Tsai CM et al., 2022 Jan, Neurophotonics
    Read more
  • Hypoxia-inducible factor 1alpha induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/beta-catenin transcriptional cofactor BCL9. Orikasa S et al., 2022 Jan 13, Sci Rep
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  • Translational relevance of behavioral, neural, and electroencephalographic profiles in a mouse model of post-traumatic stress disorder. Xi K et al., 2021 Nov, Neurobiol Stress
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  • 3,6-Dithiopomalidomide Ameliorates Hippocampal Neurodegeneration, Microgliosis and Astrogliosis and Improves Cognitive Behaviors in Rats with a Moderate Traumatic Brain Injury. Huang PS et al., 2021 Jul 31, Int J Mol Sci
    Read more
  • CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury. Ho MH et al., 2021 Oct, Redox Biol
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  • Tau Protein Phosphorylated at Threonine-231 is Expressed Abundantly in the Cerebellum in Prion Encephalopathies. Gomez-Lopez VM et al., 2021, J Alzheimers Dis
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  • Effect of Sutellarin on Neurogenesis in Neonatal Hypoxia-Ischemia Rat Model: Potential Mechanisms of Action. Xiong LL et al., 2021, Am J Chin Med
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  • Identification of highest neurotoxic amyloid-beta plaque type showing reduced contact with astrocytes. Mitsubori M et al., 2021 Apr 16, Biochem Biophys Res Commun
    Read more