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GFAP antibody

GTX108711
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGFAP
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Overview

  • Supplier
    GeneTex
  • Product Name
    GFAP antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:50000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.47 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2670
  • Target name
    GFAP
  • Target description
    glial fibrillary acidic protein
  • Target synonyms
    ALXDRD, glial fibrillary acidic protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP14136
  • Protein Name
    Glial fibrillary acidic protein
  • Scientific Description
    This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Montillot C, Skutunova E, Ayushma, et al. Characterization of Vps13b-mutant mice reveals neuroanatomical and behavioral phenotypes with females less affected. Neurobiol Dis. 2023,185:106259. doi: 10.1016/j.nbd.2023.106259
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  • Kobayashi M, Moro N, Yoshino A, et al. Inhibition of P2X4 and P2X7 receptors improves histological and behavioral outcomes after experimental traumatic brain injury in rats. Exp Ther Med. 2023,26(2):378. doi: 10.3892/etm.2023.12077
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  • Liang MZ, Lu TH, Chen L. Timely expression of PGAM5 and its cleavage control mitochondrial homeostasis during neurite re-growth after traumatic brain injury. Cell Biosci. 2023,13(1):96. doi: 10.1186/s13578-023-01052-0
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