GITR antibody [7R12]

GeneTex

GITR antibody [7R12]

9

WB: 1:500 - 1:1000. FACS: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, Western Blot, Neutralisation/Blocking

Research Use Only

Monoclonal

7R12

500 ug/ml

Unconjugated

TNFRSF18

TNF receptor superfamily member 18

AITR, CD357, ENERGEN, GITR, GITR-D, tumor necrosis factor receptor superfamily member 18, TNF receptor superfamily activation-inducible protein, activation-inducible TNFR family receptor, glucocorticoid-induced TNFR-related protein

Mouse

IgG1

Tumor necrosis factor receptor superfamily member 18

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]

Human

-20°C or -80°C,2°C to 8°C

12352203