It is possible to measure intact exendin-4 by a sandwich ELISA which is not subject to interference from GLP-1 or other glucagon-related peptides that may be present. GTX60952 is used as capture antibody in combination with a biotinylated detection antibody GTX60993-02.
It is possible to measure intact exendin-4 by a sandwich ELISA which is not subject to interference from GLP-1 or other glucagon-related peptides that may be present. GTX60952 is used as capture antibody in combination with a biotinylated detection antibody GTX60993-02.
GLP1 antibody [10]
GTX60952
Overview
- SupplierGeneTex
- Product NameGLP1 antibody [10]
- Delivery Days Customer9
- Antibody SpecificityThis antibody binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2% cross-reactivity with GLP-1(9-36)amide, glucagon and human GIP. Cross-reacts 0.25% with GLP-1(1-37), approximately 6% with human GLP-2 and approximately 50% wit
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10
- ConjugateUnconjugated
- Gene ID2641
- Target nameGCG
- Target descriptionglucagon
- Target synonymsglicentin-related polypeptide; GLP1; GLP-1; GLP2; glucagon-like peptide 1; glucagon-like peptide 2; GRPP; preproglucagon; pro-glucagon
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionThe protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203