gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)(HMB45 + PMEL/783), 1mg/mL [26628-22-8]

Biotium

gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)(HMB45 + PMEL/783), 1mg/mL [26628-22-8]

9

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

26628-22-8

Research Use Only

Monoclonal

HMB45 PMEL/783

1 mg/ml

PMEL

premelanosome protein

D12S53E, HMB-45, HMB45, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV, gp100, melanocyte protein PMEL, melanocyte protein Pmel 17, melanocyte protein mel 17, melanocytes lineage-specific antigen GP100, melanoma-associated ME20 antigen, melanosomal matrix protein17, silver locus protein homolog, silver, mouse, homolog of

Mouse

IgG1

Melanocyte protein PMEL

By immunohistochemistry, this antibody specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).

Animal

Human, Mouse

-20°C

41116161