
IHC-P analysis of human tonsil tissue using GTX24059 Granzyme B antibody.
Granzyme B antibody
GTX24059
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetGZMB
Overview
- SupplierGeneTex
- Product NameGranzyme B antibody
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3002
- Target nameGZMB
- Target descriptiongranzyme B
- Target synonymsC11; cathepsin G-like 1; CCPI; CGL1; CGL-1; CSPB; CSP-B; CTLA1; CTSGL1; cytotoxic serine protease B; cytotoxic T-lymphocyte proteinase 2; fragmentin 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); HLP; human lymphocyte protein; SECT; T-cell serine protease 1-3E
- HostRabbit
- IsotypeIgG
- Protein IDP10144
- Protein NameGranzyme B
- Scientific DescriptionThis gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203