GRK2 antibody [5D5]

GeneTex

GRK2 antibody [5D5]

9

WB: 1:100. IHC: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

5D5

Unconjugated

GRK2

G protein-coupled receptor kinase 2

ADRBK1, BARK1, BETA-ARK1, beta-adrenergic receptor kinase 1, adrenergic beta receptor kinase 1, beta-ARK-1

Mouse

IgG1

Beta-adrenergic receptor kinase 1

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203