GSK180736A

MedChem Express

GSK180736A [817194-38-0]

10

817194-38-0

Research Use Only

98.81

C19H16FN5O2

365.36

GSK180736A is potent Rho-associated coiled-coil kinase 1 (ROCK1) inhibitor with an IC 50 of 100 nM. GSK180736A is also a selective and ATP-competitive G protein-coupled receptor kinase 2 (GRK2) inhibitor with an IC 50 of 0.77 microM.

CC(N1)=C(C(NC2=CC=C(NN=C3)C3=C2)=O)C(C4=CC=C(F)C=C4)NC1=O

-20°C,2°C to 8°C

12352200