GSK180736A

AbMole BioScience

GSK180736A

9

817194-38-0

Chemical

Research Use Only

>98.0%

C19H16FN5O2

365.36

GSK180736A, developed as a Rho-associated, coiled-coil-containing protein kinase inhibitor, binds to GRK2(G protein-coupled receptor kinase 2) with logIC50 pf -6.6 (logIC50 -4.0 for GRK5 and >-3 for GRK1); ≥400-fold selective for GRK2 over both GRK1 and GRK5.

CC1=C(C(NC(=O)N1)C2=CC=C(F)C=C2)C(=O)NC3=CC4=C([NH]N=C4)C=C3

12352200