FACS analysis of HeLa cells using GTX83315 GSK3 beta antibody [3D10]. Green : GSK3 beta Purple : negative control
![ICC/IF analysis of NIH3T3 (left) and U251 (right) cells using GTX83315 GSK3 beta antibody [3D10]. Green : GSK3 beta Blue: DRAQ5 fluorescent DNA dye Red: Actin filaments](https://www.genetex.com/upload/website/prouct_img/normal/GTX83315/GTX83315_20170912_ICCIF_w_23061322_280.webp "ICC/IF analysis of NIH3T3 (left) and U251 (right) cells using GTX83315 GSK3 beta antibody [3D10]. Green : GSK3 beta Blue: DRAQ5 fluorescent DNA dye Red: Actin filaments")
![IHC-P analysis of human lung cancer (left) and breast cancer tissue (right) using GTX83315 GSK3 beta antibody [3D10].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83315/GTX83315_20170912_IHC-P_w_23061322_153.webp "IHC-P analysis of human lung cancer (left) and breast cancer tissue (right) using GTX83315 GSK3 beta antibody [3D10].")
![WB analysis of A549 (1), K562 (2), PC-12 (3), NIH3T3 (4), and HEK293 (5) cell lysate using GTX83315 GSK3 beta antibody [3D10].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83315/GTX83315_20170912_WB_w_23061322_262.webp "WB analysis of A549 (1), K562 (2), PC-12 (3), NIH3T3 (4), and HEK293 (5) cell lysate using GTX83315 GSK3 beta antibody [3D10].")
FACS analysis of HeLa cells using GTX83315 GSK3 beta antibody [3D10]. Green : GSK3 beta Purple : negative control
GSK3 beta antibody [3D10]
GTX83315
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Monkey, Mouse, Rat
TargetGSK3B
Overview
- SupplierGeneTex
- Product NameGSK3 beta antibody [3D10]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FACS: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3D10
- ConjugateUnconjugated
- Gene ID2932
- Target nameGSK3B
- Target descriptionglycogen synthase kinase 3 beta
- Target synonymsglycogen synthase kinase-3 beta; GSK-3 beta; serine/threonine-protein kinase GSK3B
- HostMouse
- IsotypeIgG2a
- Protein IDP49841
- Protein NameGlycogen synthase kinase-3 beta
- Scientific DescriptionThe protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
- ReactivityHuman, Monkey, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- GSK3beta negatively regulates TRAX, a scaffold protein implicated in mental disorders, for NHEJ-mediated DNA repair in neurons. Chien T et al., 2018 Dec, Mol PsychiatryRead more
- GSK3beta expression and phosphorylation during neuronal maturation in the rat dorsal root ganglion. Tang W et al., 2015, Int J Clin Exp MedRead more