GSK3 beta antibody

GeneTex

GSK3 beta antibody

9

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

GSK3B

glycogen synthase kinase 3 beta

glycogen synthase kinase-3 beta; GSK-3 beta; serine/threonine-protein kinase GSK3B

Chicken

IgY

Glycogen synthase kinase-3 beta

Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase. MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain. thereby reducing its affinity for DNA. Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms. alpha (GSK3A; MIM 606784) and beta. show a high degree of amino acid homology (Stambolic and Woodgett. 1994). GSK3B is involved in energy metabolism. neuronal cell development. and body pattern formation (Plyte et al.. 1992).[supplied by OMIM].

-20°C or -80°C,2°C to 8°C

12352203