ProductsBack/GSK3 beta antibody [C1C3]

GSK3 beta antibody [C1C3]

Name: GSK3 beta antibody [C1C3]
SKU: GTX111192_G10
Availability: BackOrder

GTX111192

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

DownloadDatasheet

Product group Antibodies

TargetGSK3B

Overview

Supplier
GeneTex
Product Name
GSK3 beta antibody [C1C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.57 mg/ml
Conjugate
Unconjugated
Gene ID2932
Target name
GSK3B
Target description
glycogen synthase kinase 3 beta
Target synonyms
glycogen synthase kinase-3 beta; GSK-3 beta; serine/threonine-protein kinase GSK3B
Host
Rabbit
Isotype
IgG
Protein IDP49841
Protein Name
Glycogen synthase kinase-3 beta
Scientific Description
Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase (see GYS1, MIM 138570). Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Effect of Neurorepair for Motor Functional Recovery Enhanced by Total Saponins From Trillium tschonoskii Maxim. Treatment in a Rat Model of Focal Ischemia. Yang L et al., 2021, Front Pharmacol
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The Long-Term DEHP Exposure Confers Multidrug Resistance of Triple-Negative Breast Cancer Cells through ABC Transporters and Intracellular ROS. Jadhao M et al., 2021 Jun 11, Antioxidants (Basel)
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Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis. Samuel M et al., 2021 Jun 24, Nat Commun
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Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3beta-beta-Catenin and XIAP-Survivin Pathways. Chang YX et al., 2020 Dec 21, Cancers (Basel)
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Sclareol ameliorated ERCC1-mediated cisplatin resistance in A549 human lung adenocarcinoma cells and a murine xenograft tumor model by suppressing AKT-GSK3beta-AP1/Snail and JNK-AP1 pathways. Pan CH et al., 2020 Dec 1, Chem Biol Interact
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The Role of Wnt/beta-Catenin Pathway Mediators in Aortic Valve Stenosis. Khan K et al., 2020, Front Cell Dev Biol
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The three-phase enriched environment paradigm promotes neurovascular restorative and prevents learning impairment after ischemic stroke in rats. Zhan Y et al., 2020 Dec, Neurobiol Dis
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LncRNA TTN-AS1/miR-134-5p/PAK3 axis regulates the radiosensitivity of human large intestine cancer cells through the P21 pathway and AKT/GSK-3beta/beta-catenin pathway. Zuo Z et al., 2020 Nov, Cell Biol Int
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Moscatilin Ameliorates Tau Phosphorylation and Cognitive Deficits in Alzheimers Disease Models. Huang JM et al., 2019 Jul 26, J Nat Prod
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miR-214 targets the PTEN-mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer. Liu J et al., 2017 Nov, Oncol Lett
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GSK3 beta antibody [C1C3]

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Overview

References

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