HDAC1 antibody

Name: HDAC1 antibody
SKU: GTX100513_G10
Availability: BackOrder

GTX100513

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

DownloadDatasheet

Product group Antibodies

TargetHDAC1

Overview

Supplier
GeneTex
Product Name
HDAC1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID3065
Target name
HDAC1
Target description
histone deacetylase 1
Target synonyms
GON-10; HD1; histone deacetylase 1; KDAC1; reduced potassium dependency, yeast homolog-like 1; RPD3; RPD3L1
Host
Rabbit
Isotype
IgG
Protein IDQ13547
Protein Name
Histone deacetylase 1
Scientific Description
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Acetylation of Checkpoint suppressor 1 enhances its stability and promotes the progression of triple-negative breast cancer.
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Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [(18)F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain. Claubeta O et al., 2022 Mar 8, Pharmaceuticals (Basel)
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Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45A. Lin HY et al., 2022 Jan, Biomed Pharmacother
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Deciphering genes associated with diffuse large B-cell lymphoma with lymphomatous effusions: A mutational accumulation scoring approach. Abdollahi S et al., 2021 Oct 9, Biomark Res
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PPARgamma-Induced Global H3K27 Acetylation Maintains Osteo/Cementogenic Abilities of Periodontal Ligament Fibroblasts. Yuan H et al., 2021 Aug 11, Int J Mol Sci
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Junction plakoglobin regulates and destabilizes HIF2alpha to inhibit tumorigenesis of renal cell carcinoma. Chen K et al., 2021 Apr, Cancer Commun (Lond)
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Differential Expression of Multiple Disease-Related Protein Groups Induced by Valproic Acid in Human SH-SY5Y Neuroblastoma Cells. Hu TM et al., 2020 Aug 12, Brain Sci
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Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells. Ochiai H et al., 2020 Jun, Sci Adv
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Nifedipine Exacerbates Lipogenesis in the Kidney via KIM-1, CD36, and SREBP Upregulation: Implications from an Animal Model for Human Study. Lin YC et al., 2020 Jun 19, Int J Mol Sci
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Overexpression of peptidase inhibitor 16 attenuates angiotensin II-induced cardiac fibrosis via regulating HDAC1 of cardiac fibroblasts. Deng M et al., 2020 May, J Cell Mol Med
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HDAC1 antibody

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Overview

References

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