HDAC1 antibody
GTX100513
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetHDAC1
Overview
- SupplierGeneTex
- Product NameHDAC1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3065
- Target nameHDAC1
- Target descriptionhistone deacetylase 1
- Target synonymsGON-10; HD1; histone deacetylase 1; KDAC1; reduced potassium dependency, yeast homolog-like 1; RPD3; RPD3L1
- HostRabbit
- IsotypeIgG
- Protein IDQ13547
- Protein NameHistone deacetylase 1
- Scientific DescriptionHistone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Acetylation of Checkpoint suppressor 1 enhances its stability and promotes the progression of triple-negative breast cancer.Read more
- Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [(18)F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain. Claubeta O et al., 2022 Mar 8, Pharmaceuticals (Basel)Read more
- Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45A. Lin HY et al., 2022 Jan, Biomed PharmacotherRead more
- Deciphering genes associated with diffuse large B-cell lymphoma with lymphomatous effusions: A mutational accumulation scoring approach. Abdollahi S et al., 2021 Oct 9, Biomark ResRead more
- PPARgamma-Induced Global H3K27 Acetylation Maintains Osteo/Cementogenic Abilities of Periodontal Ligament Fibroblasts. Yuan H et al., 2021 Aug 11, Int J Mol SciRead more
- Junction plakoglobin regulates and destabilizes HIF2alpha to inhibit tumorigenesis of renal cell carcinoma. Chen K et al., 2021 Apr, Cancer Commun (Lond)Read more
- Differential Expression of Multiple Disease-Related Protein Groups Induced by Valproic Acid in Human SH-SY5Y Neuroblastoma Cells. Hu TM et al., 2020 Aug 12, Brain SciRead more
- Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells. Ochiai H et al., 2020 Jun, Sci AdvRead more
- Nifedipine Exacerbates Lipogenesis in the Kidney via KIM-1, CD36, and SREBP Upregulation: Implications from an Animal Model for Human Study. Lin YC et al., 2020 Jun 19, Int J Mol SciRead more
- Overexpression of peptidase inhibitor 16 attenuates angiotensin II-induced cardiac fibrosis via regulating HDAC1 of cardiac fibroblasts. Deng M et al., 2020 May, J Cell Mol MedRead more