
WB analysis of extracts from 293 cells untreated (lane 1) or treated with EGF (lane 2) using GTX50237 HDAC4 (phospho Ser632) antibody.
HDAC4 (phospho Ser632) antibody

GTX50237
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Rat
TargetHDAC4
Overview
- SupplierGeneTex
- Product NameHDAC4 (phospho Ser632) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID9759
- Target nameHDAC4
- Target descriptionhistone deacetylase 4
- Target synonymsAHO3; BDMR; HA6116; HD4; HDAC-4; HDACA; HDAC-A; histone deacetylase 4; histone deacetylase A
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Protein IDP56524
- Protein NameHistone deacetylase 4
- Scientific DescriptionHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Catalpol ameliorates CFA-induced inflammatory pain by targeting spinal cord and peripheral inflammation. Zhao B et al., 2022, Front PharmacolRead more
- GluN2B/CaMKII mediates CFA-induced hyperalgesia via HDAC4-modified spinal COX2 transcription. Lai CY et al., 2018 Jun, NeuropharmacologyRead more
- Melatonin relieves neuropathic allodynia through spinal MT2-enhanced PP2Ac and downstream HDAC4 shuttling-dependent epigenetic modification of hmgb1 transcription. Lin TB et al., 2016 Apr, J Pineal ResRead more
- Modulation of Nerve Injury-induced HDAC4 Cytoplasmic Retention Contributes to Neuropathic Pain in Rats. Lin TB et al., 2015 Jul, AnesthesiologyRead more