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WB analysis of extracts from 293 cells untreated or treated with serum starvation using GTX50238 HDAC5 (phospho Ser498) antibody.
WB analysis of extracts from 293 cells untreated or treated with serum starvation using GTX50238 HDAC5 (phospho Ser498) antibody.
WB analysis of extracts from 293 cells untreated or treated with serum starvation using GTX50238 HDAC5 (phospho Ser498) antibody.

HDAC5 (phospho Ser498) antibody

GTX50238
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetHDAC5
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Overview

  • Supplier
    GeneTex
  • Product Name
    HDAC5 (phospho Ser498) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:1000. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10014
  • Target name
    HDAC5
  • Target description
    histone deacetylase 5
  • Target synonyms
    HD5, NY-CO-9, histone deacetylase 5, antigen NY-CO-9
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UQL6
  • Protein Name
    Histone deacetylase 5
  • Scientific Description
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    41116161

References

  • The myokine meteorin-like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPKalpha2. Lee JO et al., 2020 May, FEBS J
    Read this paper

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