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ProductsBack/HDAC6 antibody [4C5]
ICC/IF analysis of COS7 cells transiently transfected with HDAC6 plasmid using GTX84377 HDAC6 antibody [4C5].
ICC/IF analysis of COS7 cells transiently transfected with HDAC6 plasmid using GTX84377 HDAC6 antibody [4C5].
ICC/IF analysis of COS7 cells transiently transfected with HDAC6 plasmid using GTX84377 HDAC6 antibody [4C5].

HDAC6 antibody [4C5]

GTX84377
GeneTex
TargetHDAC6
DownloadDatasheet
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    HDAC6 antibody [4C5] - Overexpression Validated
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:2000. ICC/IF: 1:100. IHC-P: 1:150. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Clone ID
    4C5
  • Concentration
    0.84 mg/ml
  • Formulation
    Liquid
  • Gene ID10013
  • Target name
    HDAC6
  • Target description
    histone deacetylase 6
  • Target synonyms
    CPBHM; HD6; histone deacetylase 6; JM21; PPP1R90; protein phosphatase 1, regulatory subunit 90; tubulin-lysine deacetylase HDAC6
  • Protein IDQ9UBN7
  • Protein Name
    Histone deacetylase 6
  • Scientific Description
    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • A novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway. Huang PY et al., 2022, Am J Cancer Res
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  • A protocol to visualize cytosolic aggresome-like bodies using confocal microscopy. Kim S et al., 2021 Sep 17, STAR Protoc
    Read more
  • S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis. Zhang L et al., 2021, Cell Mol Gastroenterol Hepatol
    Read more
  • Therapeutic Effect of Modulating TREM-1 via Anti-inflammation and Autophagy in Parkinsons Disease. Feng CW et al., 2019, Front Neurosci
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  • Clinacanthus nutans Protects Cortical Neurons Against Hypoxia-Induced Toxicity by Downregulating HDAC1/6. Tsai HD et al., 2016 Sep, Neuromolecular Med
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  • Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide. He Q et al., 2014 Jun, Mol Biol Cell
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  • Characterization of an apical ceramide-enriched compartment regulating ciliogenesis. He Q et al., 2012 Aug, Mol Biol Cell
    Read more