ProductsBack/HDAC6 antibody [N1], N-term

HDAC6 antibody [N1], N-term

Name: HDAC6 antibody [N1], N-term
SKU: GTX100722_G10
Availability: BackOrder

GTX100722

ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetHDAC6

Overview

Supplier
GeneTex
Product Name
HDAC6 antibody [N1], N-term
Delivery Days Customer
9
Application Supplier Note
WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.18 mg/ml
Conjugate
Unconjugated
Gene ID10013
Target name
HDAC6
Target description
histone deacetylase 6
Target synonyms
CPBHM, HD6, JM21, KDAC6, PPP1R90, protein deacetylase HDAC6, E3 ubiquitin-protein ligase HDAC6, alpha-tubulin deacetylase HDAC6, protein phosphatase 1, regulatory subunit 90, tubulin-lysine deacetylase HDAC6
Host
Rabbit
Isotype
IgG
Protein IDQ9UBN7
Protein Name
Histone deacetylase 6
Scientific Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Semaphorin 4C promotes motility and immunosuppressive activity of cancer cells via CRMP3 and PD-L1. Hung YH et al., 2022, Am J Cancer Res
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Chondroprotective Effects of a Histone Deacetylase Inhibitor, Panobinostat, on Pain Behavior and Cartilage Degradation in Anterior Cruciate Ligament Transection-Induced Experimental Osteoarthritic Rats. Wen ZH et al., 2021 Jul 7, Int J Mol Sci
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Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells. Lee JY et al., 2016, Front Pharmacol
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A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine. Lee KH et al., 2014 Sep 17, Sci Rep
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Histone deacetylase 6 regulates estrogen receptor alpha in uterine leiomyoma. Wei LH et al., 2011 Aug, Reprod Sci
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