Bio-Connect

HDAC8 antibody [N1C2]

GTX105074
GeneTex
ApplicationsWestern Blot
Product group Antibodies
TargetHDAC8
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Overview

  • Supplier
    GeneTex
  • Product Name
    HDAC8 antibody [N1C2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID55869
  • Target name
    HDAC8
  • Target description
    histone deacetylase 8
  • Target synonyms
    CDA07, CDLS5, HD8, HDACL1, KDAC8, MRXS6, RPD3, WTS, histone deacetylase 8, histone deacetylase-like 1, protein deacetylase HDAC8, protein decrotonylase HDAC8
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9BY41
  • Protein Name
    Histone deacetylase 8
  • Scientific Description
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chen CY, Chen CC, Chuang WY, et al. Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells. Front Oncol. 2020,10:216. doi: 10.3389/fonc.2020.00216
    Read this paper