Bio-Connect

HELIOS antibody [N3C3]

GTX115629
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetIKZF2
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Overview

  • Supplier
    GeneTex
  • Product Name
    HELIOS antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID22807
  • Target name
    IKZF2
  • Target description
    IKAROS family zinc finger 2
  • Target synonyms
    ANF1A2; HELIOS; ikaros family zinc finger protein 2; zinc finger DNA binding protein Helios; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; ZNFN1A2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UKS7
  • Protein Name
    Zinc finger protein Helios
  • Scientific Description
    This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • In Situ Characterization of Human Lymphoid Tissue Immune Cells by Multispectral Confocal Imaging and Quantitative Image Analysis; Implications for HIV Reservoir Characterization. Moysi E et al., 2021, Front Immunol
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  • Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination. Amodio D et al., 2018 Jan 15, J Immunol
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  • Clinical significance of expanded Foxp3+ Helios- regulatory T cells in patients with non-small cell lung cancer. Muto S et al., 2015 Dec, Int J Oncol
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