Her4 / ErbB4 antibody

GeneTex

Her4 / ErbB4 antibody

9

IHC-P: Use at a dilution of 1/50 for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. WB: Use at an assay dependent dilution. Predicted molecular weight: 146.8 kDa. Optimal dilutions/concentrations should be determined by the end user.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.2 mg/ml

Unconjugated

ERBB4

erb-b2 receptor tyrosine kinase 4

ALS19, HER4, p180erbB4, receptor tyrosine-protein kinase erbB-4, avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, human epidermal growth factor receptor 4, proto-oncogene-like protein c-ErbB-4, tyrosine kinase-type cell surface receptor HER4, v-erb-a erythroblastic leukemia viral oncogene homolog 4, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Rabbit

IgG

Receptor tyrosine-protein kinase erbB-4

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

2°C to 8°C

12352203