Her4 / ErbB4 antibody [HFR1]

GeneTex

Her4 / ErbB4 antibody [HFR1]

9

WB: 1:100-1:500. ICC/IF: 1:50. IHC-P: 1:100. FACS: 0.5-2 microg/test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

HFR1

1 mg/ml

Liquid

ERBB4

erb-b2 receptor tyrosine kinase 4

ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; HER4; human epidermal growth factor receptor 4; p180erbB4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine-protein kinase erbB-4; tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Receptor tyrosine-protein kinase erbB-4

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203