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Hexokinase II antibody

GTX111525
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetHK2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Hexokinase II antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.63 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3099
  • Target name
    HK2
  • Target description
    hexokinase 2
  • Target synonyms
    hexokinase type II; hexokinase-2; hexokinase-2, muscle; hexokinase-B; HKII; HXK2; muscle form hexokinase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP52789
  • Protein Name
    Hexokinase-2
  • Scientific Description
    Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders. Baryla I et al., 2022 Mar 19, Int J Mol Sci
    Read more
  • Calcitriol Suppresses Warburg Effect and Cell Growth in Human Colorectal Cancer Cells. Huang CY et al., 2021 Sep 14, Life (Basel)
    Read more
  • Glycometabolic Regulation of the Biogenesis of Small Extracellular Vesicles. Harada Y et al., 2020 Oct 13, Cell Rep
    Read more
  • Regulation of autophagy, glucose uptake, and glycolysis under dengue virus infection. Lee YR et al., 2020 Nov, Kaohsiung J Med Sci
    Read more
  • The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells. Takino JI et al., 2019 Nov 13, Sci Rep
    Read more
  • Adenine Nucleotide Translocase 2 as an Enzyme Related to [18F] FDG Accumulation in Various Cancers. Lee CH et al., 2019 Aug, Mol Imaging Biol
    Read more
  • PIM2-mediated phosphorylation of hexokinase 2 is critical for tumor growth and paclitaxel resistance in breast cancer. Yang T et al., 2018 Nov, Oncogene
    Read more
  • Proteomic analysis of oral cancer reveals new potential therapeutic targets involved in the Warburg effect. Huang YP et al., 2017 Aug, Clin Exp Pharmacol Physiol
    Read more

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