Hexokinase II antibody
GTX111525
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetHK2
Overview
- SupplierGeneTex
- Product NameHexokinase II antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.63 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID3099
- Target nameHK2
- Target descriptionhexokinase 2
- Target synonymshexokinase type II; hexokinase-2; hexokinase-2, muscle; hexokinase-B; HKII; HXK2; muscle form hexokinase
- HostRabbit
- IsotypeIgG
- Protein IDP52789
- Protein NameHexokinase-2
- Scientific DescriptionHexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- The WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders. Baryla I et al., 2022 Mar 19, Int J Mol SciRead more
- Calcitriol Suppresses Warburg Effect and Cell Growth in Human Colorectal Cancer Cells. Huang CY et al., 2021 Sep 14, Life (Basel)Read more
- Glycometabolic Regulation of the Biogenesis of Small Extracellular Vesicles. Harada Y et al., 2020 Oct 13, Cell RepRead more
- Regulation of autophagy, glucose uptake, and glycolysis under dengue virus infection. Lee YR et al., 2020 Nov, Kaohsiung J Med SciRead more
- The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells. Takino JI et al., 2019 Nov 13, Sci RepRead more
- Adenine Nucleotide Translocase 2 as an Enzyme Related to [18F] FDG Accumulation in Various Cancers. Lee CH et al., 2019 Aug, Mol Imaging BiolRead more
- PIM2-mediated phosphorylation of hexokinase 2 is critical for tumor growth and paclitaxel resistance in breast cancer. Yang T et al., 2018 Nov, OncogeneRead more
- Proteomic analysis of oral cancer reveals new potential therapeutic targets involved in the Warburg effect. Huang YP et al., 2017 Aug, Clin Exp Pharmacol PhysiolRead more