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IHC-P analysis of human lung tissue using GTX42614 HEY1 antibody at 4.0-8.0microg/ml.
IHC-P analysis of human lung tissue using GTX42614 HEY1 antibody at 4.0-8.0microg/ml.
IHC-P analysis of human lung tissue using GTX42614 HEY1 antibody at 4.0-8.0microg/ml.

HEY1 antibody, C-term

GTX42614
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetHEY1
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Overview

  • Supplier
    GeneTex
  • Product Name
    HEY1 antibody, C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 0.2-2.5 ug/ml. IHC-P: 2-10 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5-1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23462
  • Target name
    HEY1
  • Target description
    hes related family bHLH transcription factor with YRPW motif 1
  • Target synonyms
    basic helix-loop-helix protein OAF1; BHLHb31; cardiovascular helix-loop-helix factor 2; CHF2; class B basic helix-loop-helix protein 31; hairy and enhancer of split-related protein 1; hairy/enhancer-of-split related with YRPW motif 1; hairy/enhancer-of-split related with YRPW motif protein 1; hairy-related transcription factor 1; HERP2; HESR1; HES-related repressor protein 1; HES-related repressor protein 2; hHRT1; HRT-1; NERP2; OAF1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y5J3
  • Protein Name
    Hairy/enhancer-of-split related with YRPW motif protein 1
  • Scientific Description
    This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Converting melanoma-associated fibroblasts into a tumor-suppressive phenotype by increasing intracellular Notch1 pathway activity. Shao H et al., 2021, PLoS One
    Read more
  • Notch1 Pathway Activity Determines the Regulatory Role of Cancer-Associated Fibroblasts in Melanoma Growth and Invasion. Shao H et al., 2015, PLoS One
    Read more
  • Inhibition of fibroblast growth by Notch1 signaling is mediated by induction of Wnt11-dependent WISP-1. Liu ZJ et al., 2012, PLoS One
    Read more
  • Activation of Notch1 signaling in stromal fibroblasts inhibits melanoma growth by upregulating WISP-1. Shao H et al., 2011 Oct 20, Oncogene
    Read more

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