
IHC-P analysis of human lung tissue using GTX42614 HEY1 antibody at 4.0-8.0microg/ml.
HEY1 antibody, C-term
GTX42614
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetHEY1
Overview
- SupplierGeneTex
- Product NameHEY1 antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. IHC-P: 2-10 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID23462
- Target nameHEY1
- Target descriptionhes related family bHLH transcription factor with YRPW motif 1
- Target synonymsbasic helix-loop-helix protein OAF1; BHLHb31; cardiovascular helix-loop-helix factor 2; CHF2; class B basic helix-loop-helix protein 31; hairy and enhancer of split-related protein 1; hairy/enhancer-of-split related with YRPW motif 1; hairy/enhancer-of-split related with YRPW motif protein 1; hairy-related transcription factor 1; HERP2; HESR1; HES-related repressor protein 1; HES-related repressor protein 2; hHRT1; HRT-1; NERP2; OAF1
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y5J3
- Protein NameHairy/enhancer-of-split related with YRPW motif protein 1
- Scientific DescriptionThis gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Converting melanoma-associated fibroblasts into a tumor-suppressive phenotype by increasing intracellular Notch1 pathway activity. Shao H et al., 2021, PLoS OneRead more
- Notch1 Pathway Activity Determines the Regulatory Role of Cancer-Associated Fibroblasts in Melanoma Growth and Invasion. Shao H et al., 2015, PLoS OneRead more
- Inhibition of fibroblast growth by Notch1 signaling is mediated by induction of Wnt11-dependent WISP-1. Liu ZJ et al., 2012, PLoS OneRead more
- Activation of Notch1 signaling in stromal fibroblasts inhibits melanoma growth by upregulating WISP-1. Shao H et al., 2011 Oct 20, OncogeneRead more