HGS antibody [C2C3], C-term
GTX101718
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetHGS
Overview
- SupplierGeneTex
- Product NameHGS antibody [C2C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9146
- Target nameHGS
- Target descriptionhepatocyte growth factor-regulated tyrosine kinase substrate
- Target synonymshepatocyte growth factor-regulated tyrosine kinase substrate; HRS; human growth factor-regulated tyrosine kinase substrate; protein pp110
- HostRabbit
- IsotypeIgG
- Protein IDO14964
- Protein NameHepatocyte growth factor-regulated tyrosine kinase substrate
- Scientific DescriptionThe protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes. Larios J et al., 2020 Mar 2, J Cell BiolRead more
- Growth factor stimulation promotes multivesicular endosome biogenesis by prolonging recruitment of the late-acting ESCRT machinery. Quinney KB et al., 2019 Apr 2, Proc Natl Acad Sci U S ARead more
- The Dual Role of an ESCRT-0 Component HGS in HBV Transcription and Naked Capsid Secretion. Chou SF et al., 2015 Oct, PLoS PathogRead more
- Essential role of endocytosis for interleukin-4-receptor-mediated JAK/STAT signalling. Kurgonaite K et al., 2015 Oct 15, J Cell SciRead more
- A high-throughput approach for measuring temporal changes in the interactome. Kristensen AR et al., 2012 Sep, Nat MethodsRead more
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