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ICC/IF analysis of HepG2 cells using GTX84311 HIPPI antibody [2G3].
ICC/IF analysis of HepG2 cells using GTX84311 HIPPI antibody [2G3].
ICC/IF analysis of HepG2 cells using GTX84311 HIPPI antibody [2G3].

HIPPI antibody [2G3]

GTX84311
GeneTex
TargetIFT57
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    HIPPI antibody [2G3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:2000. ICC/IF: 1:100. IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Clone ID
    2G3
  • Concentration
    0.71 mg/ml
  • Formulation
    Liquid
  • Gene ID55081
  • Target name
    IFT57
  • Target description
    intraflagellar transport 57
  • Target synonyms
    dermal papilla-derived protein 8; ESRRBL1; estrogen-related receptor beta like 1; estrogen-related receptor beta-like protein 1; HIP1 protein interactor; HIP1-interacting protein; HIPPI; huntingtin interacting protein-1 interacting protein; intraflagellar transport 57 homolog; intraflagellar transport protein 57 homolog; MHS4R2; OFD18
  • Protein IDQ9NWB7
  • Protein Name
    Intraflagellar transport protein 57 homolog
  • Scientific Description
    Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5-AAAGACATG-3 present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator - however the relevance of such function remains unclear.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203