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GTX111124 IHC-P Image
GTX111124 IHC-P Image
GTX111124 IHC-P Image

HIPPI antibody [N1C3]

Research Use Only
GTX111124
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    HIPPI antibody [N1C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.52 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5-AAAGACATG-3 present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203