HIPPI antibody [N1C3]
![Research Use Only](static/images/certificates/ruo.jpg)
GTX111124
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetIFT57
Overview
- SupplierGeneTex
- Product NameHIPPI antibody [N1C3]
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.52 mg/ml
- ConjugateUnconjugated
- Gene ID55081
- Target nameIFT57
- Target descriptionintraflagellar transport 57
- Target synonymsdermal papilla-derived protein 8; ESRRBL1; estrogen-related receptor beta like 1; estrogen-related receptor beta-like protein 1; HIP1 protein interactor; HIP1-interacting protein; HIPPI; huntingtin interacting protein-1 interacting protein; intraflagellar transport 57 homolog; intraflagellar transport protein 57 homolog; MHS4R2; OFD18
- HostRabbit
- IsotypeIgG
- Scientific DescriptionRequired for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5-AAAGACATG-3 present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203