Western blot analysis of extracts of various cell lines using HLA-DPB1 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using HLA-DPB1 Polyclonal Antibody at dilution of 1:1000.
HLA-DPB1 Polyclonal Antibody
E-AB-60306
Product group Antibodies
Overview
- SupplierElabscience
- Product NameHLA-DPB1 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionHLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
- UNSPSC12352203