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Western Blot Positive WB detected in: 293 whole cell lysate All lanes: HMGB3 antibody at 7microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 23 kDa Observed band size: 23 kDa
Western Blot Positive WB detected in: 293 whole cell lysate All lanes: HMGB3 antibody at 7microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 23 kDa Observed band size: 23 kDa
Western Blot Positive WB detected in: 293 whole cell lysate All lanes: HMGB3 antibody at 7microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 23 kDa Observed band size: 23 kDa

HMGB3 Antibody

CSB-PA010561LA01HU
Cusabio
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetHMGB3
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Overview

  • Supplier
    Cusabio
  • Product Name
    HMGB3 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID3149
  • Target name
    HMGB3
  • Target description
    high mobility group box 3
  • Target synonyms
    HMG-2a, HMG-4, HMG2A, HMG4, high mobility group protein B3, high mobility group protein 2a, high-mobility group (nonhistone chromosomal) protein 4
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO15347
  • Protein Name
    High mobility group protein B3
  • Scientific Description
    Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161