
Western Blot Positive WB detected in: 293 whole cell lysate All lanes: HMGB3 antibody at 7microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 23 kDa Observed band size: 23 kDa
HMGB3 Antibody
CSB-PA010561LA01HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetHMGB3
Overview
- SupplierCusabio
- Product NameHMGB3 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3149
- Target nameHMGB3
- Target descriptionhigh mobility group box 3
- Target synonymsHMG-2a, HMG-4, HMG2A, HMG4, high mobility group protein B3, high mobility group protein 2a, high-mobility group (nonhistone chromosomal) protein 4
- HostRabbit
- IsotypeIgG
- Protein IDO15347
- Protein NameHigh mobility group protein B3
- Scientific DescriptionMultifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161









