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HMGCS1 antibody

GTX112346
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetHMGCS1
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Overview

  • Supplier
    GeneTex
  • Product Name
    HMGCS1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.39 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3157
  • Target name
    HMGCS1
  • Target description
    3-hydroxy-3-methylglutaryl-CoA synthase 1
  • Target synonyms
    HMGCS, hydroxymethylglutaryl-CoA synthase, cytoplasmic, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase, 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble), 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ01581
  • Protein Name
    Hydroxymethylglutaryl-CoA synthase, cytoplasmic
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Nakahara R, Aki S, Sugaya M, et al. Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth. EMBO J. 2023,42(22):e114032. doi: 10.15252/embj.2023114032
    Read this paper
  • Han B, Alonso-Valenteen F, Wang Z, et al. A chemokine regulatory loop induces cholesterol synthesis in lung-colonizing triple-negative breast cancer cells to fuel metastatic growth. Mol Ther. 2022,30(2):672-687. doi: 10.1016/j.ymthe.2021.07.003
    Read this paper
  • Wang IH, Huang TT, Chen JL, et al. Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression. Cancers (Basel). 2020,12(5). doi: 10.3390/cancers12051088
    Read this paper
  • Lupo MG, Biancorosso N, Brilli E, et al. Cholesterol-Lowering Action of a Novel Nutraceutical Combination in Uremic Rats: Insights into the Molecular Mechanism in a Hepatoma Cell Line. Nutrients. 2020,12(2). doi: 10.3390/nu12020436
    Read this paper

Datasheet

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