More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/HMGCS1 antibody

HMGCS1 antibody

GTX112346
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetHMGCS1
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    HMGCS1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.39 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3157
  • Target name
    HMGCS1
  • Target description
    3-hydroxy-3-methylglutaryl-CoA synthase 1
  • Target synonyms
    HMGCS, hydroxymethylglutaryl-CoA synthase, cytoplasmic, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase, 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble), 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ01581
  • Protein Name
    Hydroxymethylglutaryl-CoA synthase, cytoplasmic
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth.
    Read more
  • A chemokine regulatory loop induces cholesterol synthesis in lung-colonizing triple-negative breast cancer cells to fuel metastatic growth. Han B et al., 2022 Feb 2, Mol Ther
    Read more
  • Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression. Wang IH et al., 2020 Apr 27, Cancers (Basel)
    Read more
  • Cholesterol-Lowering Action of a Novel Nutraceutical Combination in Uremic Rats: Insights into the Molecular Mechanism in a Hepatoma Cell Line. Lupo MG et al., 2020 Feb 9, Nutrients
    Read more

Datasheet

Download Datasheet

FAQ

Go to our frequently asked questions

Related products

IHC image of CSB-PA010566LA01HU diluted at 1:500 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Product group Antibodies
Cusabio
HMGCS1 AntibodyCSB-PA010566LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
ReactivityHuman
TargetHMGCS1
  • SizePrice
Product group Antibodies
Assay Genie
HMGCS1 AntibodyCAB3916
TargetHMGCS1
  • SizePrice
WB analysis of various sample lysates using GTX64522 HMGCS1 antibody. Dilution : 1:7000 Loading : 25microg per lane
Product group Antibodies
GeneTex
HMGCS1 antibodyGTX64522
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
TargetHMGCS1
  • SizePrice
Product group Antibodies
Everest Biotech
Goat anti-HMGCS1EB12867
ApplicationsWestern Blot, ELISA
TargetHMGCS1
  • SizePrice
IHC-P analysis of human skeletal muscle tissue using GTX46215 HMGCS1 antibody at 5microg/ml.
Product group Antibodies
GeneTex
HMGCS1 antibody, InternalGTX46215
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetHMGCS1
  • SizePrice
Product group Antibodies
Bethyl Laboratories
Rabbit anti-HMGCS1 Antibody, Affinity PurifiedA304-590A
ApplicationsImmunoPrecipitation, Western Blot
TargetHMGCS1
  • SizePrice
Product group Antibodies
RayBiotech
Anti-HMGCS1 Antibody144-03916
ApplicationsWestern Blot
TargetHMGCS1
  • SizePrice
Anti-HMGCS1 Antibody
Product group Antibodies
Antibodies.com
Anti-HMGCS1 AntibodyA9326
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • SizePrice
Figure 1. Western blot analysis of HMGCS1 using anti-HMGCS1 antibody (A05313-2). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: human HepG2 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-HMGCS1 antigen affinity purified polyclonal antibody (Catalog # A05313-2) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for HMGCS1 at approximately 57 kDa. The expected band size for HMGCS1 is at 57 kDa.
Product group Antibodies
Boster Bio
Anti-HMGCS1 Antibody Picoband(r)A05313-2-CARRIER-FREE
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetHMGCS1
  • SizePrice
Product group Antibodies
Biomatik
HMGCS1 Polyclonal AntibodyCAC13079
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
TargetHMGCS1
  • SizePrice