hnRNP A2B1 antibody
GTX127928
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetHNRNPA2B1
Overview
- SupplierGeneTex
- Product NamehnRNP A2B1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.09 mg/ml
- ConjugateUnconjugated
- Gene ID3181
- Target nameHNRNPA2B1
- Target descriptionheterogeneous nuclear ribonucleoprotein A2/B1
- Target synonymsHNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, OPMD2, RNPA2, SNRPB1, heterogeneous nuclear ribonucleoproteins A2/B1, HNRNPA2B1/MYC fusion, epididymis secretory sperm binding protein, hnRNP A2 / hnRNP B1, nuclear ribonucleoprotein particle A2 protein
- HostRabbit
- IsotypeIgG
- Protein IDP22626
- Protein NameHeterogeneous nuclear ribonucleoproteins A2/B1
- Scientific DescriptionThis gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Lu SH, Lee KZ, Hsu PW, et al. Alternative Splicing Mediated by RNA-Binding Protein RBM24 Facilitates Cardiac Myofibrillogenesis in a Differentiation Stage-Specific Manner. Circ Res. 2022,130(1):112-129. doi: 10.1161/CIRCRESAHA.121.320080Read this paper
- Liu YJ, Kuo HC, Chern Y. A system-wide mislocalization of RNA-binding proteins in motor neurons is a new feature of ALS. Neurobiol Dis. 2021,160:105531. doi: 10.1016/j.nbd.2021.105531Read this paper
- Chen JF, Tsai YT, Lai YH, et al. Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells. J Pharm Biomed Anal. 2020,187:113142. doi: 10.1016/j.jpba.2020.113142Read this paper
- Wang J, Ganaie SS, Cheng F, et al. RNA Binding Motif Protein RBM45 Regulates Expression of the 11-Kilodalton Protein of Parvovirus B19 through Binding to Novel Intron Splicing Enhancers. mBio. 2020,11(2). doi: 10.1128/mBio.00192-20Read this paper
- Fang MY, Markmiller S, Vu AQ, et al. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron. 2019,103(5):802-819.e11. doi: 10.1016/j.neuron.2019.05.048Read this paper
- Yu HI, Chou HC, Su YC, et al. Proteomic analysis of evodiamine-induced cytotoxicity in thyroid cancer cells. J Pharm Biomed Anal. 2018,160:344-350. doi: 10.1016/j.jpba.2018.08.008Read this paper
- Zhang J, Kong L, Guo S, et al. hnRNPs and ELAVL1 cooperate with uORFs to inhibit protein translation. Nucleic Acids Res. 2017,45(5):2849-2864. doi: 10.1093/nar/gkw991Read this paper
- Sundararaman B, Zhan L, Blue SM, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016,61(6):903-13. doi: 10.1016/j.molcel.2016.02.012Read this paper




