Hsp47 Antibody (OASE00148)

Aviva Systems Biology

Hsp47 Antibody (OASE00148)

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

1C4-1A6

1 mg/ml

Unconjugated

Liquid PBS (pH 7.4) with 50% glycerol and 0.09% sodium azide

SERPINH1

serpin family H member 1

AsTP3, CBP1, CBP2, HSP47, OI10, PIG14, PPROM, RA-A47, SERPINH2, gp46, serpin H1, 47 kDa heat shock protein, arsenic-transactivated protein 3, cell proliferation-inducing gene 14 protein, collagen binding protein 1, colligin-1, colligin-2, heat shock protein 47, rheumatoid arthritis antigen A-47, rheumatoid arthritis-related antigen RA-A47, serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1), serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2), serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

Mouse

IgG1

HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions (1). The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate (2). Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils (3).

-20°C

12352203