WB analysis of various sample lysates using GTX64430 HYPB/SETD2 antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX64430 HYPB/SETD2 antibody. Dilution : 1:1000 Loading : 25microg per lane
HYPB/SETD2 antibody
GTX64430
Overview
- SupplierGeneTex
- Product NameHYPB/SETD2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID29072
- Target nameSETD2
- Target descriptionSET domain containing 2, histone lysine methyltransferase
- Target synonymsHBP231; HIF-1; HIP-1; histone-lysine N-methyltransferase SETD2; HSPC069; huntingtin interacting protein 1; huntingtin yeast partner B; huntingtin-interacting protein B; HYPB; KMT3A; LLS; lysine N-methyltransferase 3A; p231HBP; protein-lysine N-methyltransferase SETD2; SET2
- HostRabbit
- IsotypeIgG
- Protein IDQ9BYW2
- Protein NameHistone-lysine N-methyltransferase SETD2
- Scientific DescriptionHuntingtons disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203